In Vitro Immunogenicity Assessment: Perspective from a CRO (S03-3)

This presentation will offer the perspective from a CRO providing a wide range of immunogenicity assays for a broad range of therapeutic protein products.  We will focus on the use of MAPPs for assessment of unwanted immunogenicity and the importance of primary cell quality and culture conditions in combination with state-of-the-art purification of MHC complexes and ultrasensitive MS analysis of immunopeptides.